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Natrapharm
Regulatory Class: Rx
C: Pyrazinamide
I: As part of multidrug regimen for all forms of pulmonary & extrapulmonary TB.
D: Adult & childn 35 mg/kg daily, max daily dose of 3 g or 50 mg/kg 3x a wk or 75 mg/kg twice wkly. Partial intermittent therapy: Administer w/ INH & rifampicin daily for the 1st 2 mth. Afterwards, treatment w/ INH & rifampicin will continue for the next 4 mth.
A:
CI: Liver damage.
SP: Impaired renal function or a history of gout. DM. Pregnancy & lactation.
