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Product Specialties - Anti-Depressant

Trimipramine
SURMONTIL®

Presentation:

Tablets contain the equivalent of 25mg trimipramine (as maleate).

Indications:

Depressive illness, especially if accompanied by sleep disturbance, anxiety or agitation.

Dosage:

Mild/moderate depression: 25-75mg at night or in divided doses. Increase if necessary to 150-300mg/day. Reduce to normal maintenance level of 75-150mg/day. Not recommended for children.

Contraindications:

Recent myocardial infarction, heart block, cardiac arrhythmia, mania, severe liver disease, breastfeeding.

Precautions:

Narrow-angle glaucoma, prostatic hypertrophy, epilepsy, high suicidal risk patients, anesthesia,use in pregnancy not recommended unless essential, withdrawal symptoms on abrupt cessation of treatment. Concurrent use with sympathomimetic agents and mon-aminoxidase inhibitors.

Side Effects:

Sedating, dry mouth, impaired accommodation, tachycardia, constipation, micturition disturbance, potentiation of the effects of alcohol, sweating, postural hypotension, tremor, skin rash, impaired renal function. Rarely blood dyscrasia, cholestatic jaundice, hypomania, convulsions, peripheral neuropathy.

Cautions:

Foods, Drugs, Devices and Cosmetic Act prohibits dispensing without prescription.

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